NEUROMUSCULAR SENSITIVITY TO TUBOCURARINE A comparison of 10 parameters
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چکیده
منابع مشابه
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متن کاملThe actions of tubocurarine at the frog neuromuscular junction.
1. The action of tubocurarine on voltage-clamped frog muscle end-plates has been re-examined by means (a) equilibrium dose-ratio measurements, (b) current fluctuation measurements and (c) voltage-jump relaxation measurements. 2. The equilibrium measurements can be interpreted as implying that tubocurarine has (a) a competitive blocking action, with a dissociation constant of 0.34 microM, which ...
متن کاملFailure of neostigmine to prevent tubocurarine neuromuscular block in the isolated arm.
Neostigmine failed to modify the development of neuromuscular block in the presence of a high local concentration of tubocurarine. Only when the concentration of tubocurarine was reduced, and a suitable concentration gradient established between the receptor area and the plasma, did neostigmine increase the rate of recovery from the action of non-depolarizing neuromuscular blocking agents.
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1976
ISSN: 0007-0912
DOI: 10.1093/bja/48.11.1045